Anti-GABA A Receptor delta 抗体 [N151/3] (ab93619)

製品の概要

  • 製品名
    Anti-GABA A Receptor delta antibody [N151/3]
    GABA A Receptor delta 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [N151/3] to GABA A Receptor delta
  • 由来種
    Mouse
  • 特異性
    GABA A receptor delta
  • アプリケーション
    適用あり: WB, ICCmore details
  • 種交差性
    交差種: Mouse, Rat
    交差が予測される動物種: Cow
  • 免疫原

    Synthetic peptide:

    CTQPHHGARAMNDIGDYVGSN

    , corresponding to amino acids 15-34 of Rat GABA A Receptor delta

  • ポジティブ・コントロール
    • Rat brain lysate
  • 特記事項

    The clone number has been updated from S151-3 to N151/3, both clone numbers name the same antibody clone.

     

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ICC
  • 追加情報
    ICC: Use at a concentration of 0.1 - 1 µg/ml.
    WB: Use at a concentration of 1 - 10 µg/ml. Predicted molecular weight: 51 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
    • 関連疾患
      Defects in GABRD are the cause of susceptibility to generalized epilepsy with febrile seizures plus type 5 (GEFS+5) [MIM:604233]. Generalized epilepsy with febrile seizures-plus refers to a rare familial condition with incomplete penetrance and large intrafamilial variability. Patients display febrile seizures persisting sometimes beyond the age of 6 years and/or a variety of afebrile seizure types. GEFS+ is a disease combining febrile seizures, generalized seizures often precipitated by fever at age 6 years or more, and partial seizures, with a variable degree of severity.
      Defects in GABRD are the cause of susceptibility to idiopathic generalized epilepsy type 10 (IGE10) [MIM:613060]. A disorder characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain.
      Defects in GABRD are the cause of susceptibility to juvenile myoclonic epilepsy type 7 (EJM7) [MIM:613060]. A subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.
    • 配列類似性
      Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRD sub-subfamily.
    • 細胞内局在
      Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • GABA(A) receptor subunit delta antibody
      • Gabrd antibody
      • Gamma aminobutyric acid GABA A receptor delta antibody
      • Gamma aminobutyric acid receptor delta subunit precursor GABA A receptor antibody
      • Gamma-aminobutyric acid receptor subunit delta antibody
      • GBRD_HUMAN antibody
      • MGC45284 antibody
      see all

    参考文献

    ab93619 has not yet been referenced specifically in any publications.

    レビューと Q&A

    Application
    Immunohistochemistry (PFA perfusion fixed frozen sections)
    Sample
    Rat Tissue sections (Brain)
    Antigen retrieval step
    None
    Permeabilization
    No
    Specification
    Brain
    Blocking step
    Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 24°C
    Fixative
    Paraformaldehyde
    Username

    Mrs. Olga Cravetchi

    Verified customer

    投稿 Jul 12 2016

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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