Anti-GABA A Receptor delta 抗体 (ab110014)

製品の概要

  • 製品名Anti-GABA A Receptor delta antibody
    GABA A Receptor delta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GABA A Receptor delta
  • 特異性Detects endogenous levels of total GABA A Receptor delta protein
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthesized peptide derived from an internal sequence of human GABA A Receptor delta

  • ポジティブ・コントロール
    • Extracts from LOVO or HT29 cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 50 kDa.

ターゲット情報

  • 機能GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 関連疾患Defects in GABRD are the cause of susceptibility to generalized epilepsy with febrile seizures plus type 5 (GEFS+5) [MIM:604233]. Generalized epilepsy with febrile seizures-plus refers to a rare familial condition with incomplete penetrance and large intrafamilial variability. Patients display febrile seizures persisting sometimes beyond the age of 6 years and/or a variety of afebrile seizure types. GEFS+ is a disease combining febrile seizures, generalized seizures often precipitated by fever at age 6 years or more, and partial seizures, with a variable degree of severity.
    Defects in GABRD are the cause of susceptibility to idiopathic generalized epilepsy type 10 (IGE10) [MIM:613060]. A disorder characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain.
    Defects in GABRD are the cause of susceptibility to juvenile myoclonic epilepsy type 7 (EJM7) [MIM:613060]. A subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.
  • 配列類似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRD sub-subfamily.
  • 細胞内局在Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • GABA(A) receptor subunit delta antibody
    • Gabrd antibody
    • Gamma aminobutyric acid GABA A receptor delta antibody
    • Gamma aminobutyric acid receptor delta subunit precursor GABA A receptor antibody
    • Gamma-aminobutyric acid receptor subunit delta antibody
    • GBRD_HUMAN antibody
    • MGC45284 antibody
    see all

Anti-GABA A Receptor delta antibody 画像

  • All lanes : Anti-GABA A Receptor delta antibody (ab110014) at 1/500 dilution

    Lane 1 : extracts from HT29 cells (5-30 ug total protein) with no immunizing peptide
    Lane 2 : extracts from LOVO cells (5-30 ug total protein) with no immunizing peptide
    Lane 3 : extracts from LOVO cells (5-30 ug total protein) with immunizing peptide (5-10 ug)


    Predicted band size : 50 kDa

Anti-GABA A Receptor delta antibody (ab110014) 使用論文

ab110014 has not yet been referenced specifically in any publications.

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