製品の概要

  • 製品名Anti-GAB1 (phospho Y659) antibody
    GAB1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to GAB1 (phospho Y659)
  • 特異性This antibody detects endogenous levels of GAB1 only when phosphorylated at tyrosine 659. Human: Tyr659; Mouse: Tyr660.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic phosphopeptide derived from human GAB1 around the phosphorylation site of tyrosine 659 (VDYPVV).

  • ポジティブ・コントロール
    • NIH/3T3 cell extracts

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab59410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 77 kDa (predicted molecular weight: 77 kDa).
ELISA 1/5000.

ターゲット情報

  • 機能Probably involved in EGF and insulin receptor signaling.
  • 配列類似性Belongs to the GAB family.
    Contains 1 PH domain.
  • 翻訳後修飾Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Gab 1 antibody
    • GAB1 antibody
    • GAB1_HUMAN antibody
    • GRB 2 associated binder 1 antibody
    • GRB 2 associated binding protein 1 antibody
    • GRB2 associated binding protein 1 isoform a antibody
    • GRB2 associated binding protein 1 isoform b antibody
    • GRB2-associated binder 1 antibody
    • GRB2-associated-binding protein 1 antibody
    • Growth factor receptor bound protein 2-associated protein 1 antibody
    see all

Anti-GAB1 (phospho Y659) antibody 画像

  • All lanes : Anti-GAB1 (phospho Y659) antibody (ab59410) at 1/500 dilution

    Lane 1 : NIH/3T3 cells, treated with Insulin (0.01U/ml, 15mins)
    Lane 2 : NIH/3T3 cells, treated with Insulin (0.01U/ml, 15mins) with immunizing phosphopeptide


    Predicted band size : 77 kDa
    Observed band size : 77 kDa

Anti-GAB1 (phospho Y659) antibody (ab59410) 使用論文

ab59410 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"