機能Probably involved in EGF and insulin receptor signaling.
配列類似性Belongs to the GAB family. Contains 1 PH domain.
翻訳後修飾Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
ab32093 at a 1:50 dilution staining GAB1 in PC-12 cells using immunofluoresence
Anti-GAB1 antibody [Y423] (ab32093) 使用論文
This product has been referenced in:
Le Goff A et al. Anti-apoptotic Role of Caspase-cleaved GAB1 Adaptor Protein in Hepatocyte Growth Factor/Scatter Factor-MET Receptor Protein Signaling. J Biol Chem287:35382-96 (2012).
Read more (PubMed: 22915589) »