G Protein alpha Inhibitor 1+2 peptide (ab5006)

製品の概要

  • 製品名G Protein alpha Inhibitor 1+2 peptide

製品の詳細

  • 由来Synthetic

特性

Our Abpromise guarantee covers the use of ab5006 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 製品の状態Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human G protein alpha inhibitor 1/2, catalog ab3522. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Adenylate cyclase-inhibiting G alpha protein
    • Gi
    • Gi1 protein alpha subunit
    • Gi2 protein alpha subunit
    • GIP
    • GNAI1
    • GNAI1_HUMAN
    • GNAI2
    • GNAI2B
    • Guanine nucleotide binding protein G(i) alpha 1 subunit
    • Guanine nucleotide binding protein G(i) alpha 2 subunit
    • Guanine nucleotide-binding protein G(i) subunit alpha-1
    see all
  • 機能Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
  • 配列類似性Belongs to the G-alpha family. G(i/o/t/z) subfamily.
  • 細胞内局在Nucleus. Cytoplasm. Cell membrane. Cytoplasm > cytoskeleton > centrosome. Localized at the plasma membrane throughout mitosis. Colocalizes with RIC8A and RGS14 at the plasma membrane (By similarity). Localizes in the centrosomes of interphase and mitotic cells, but not in centrosomes during cytokinesis. Detected at the cleavage furrow or the midbody.
  • Information by UniProt

G Protein alpha Inhibitor 1+2 peptide (ab5006) 使用論文

ab5006 has not yet been referenced specifically in any publications.

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