製品の概要

  • 製品名Anti-FYB antibody
    FYB 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FYB
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Dog
  • 免疫原

    Synthetic peptide, corresponding to a region within C terminal amino acids 692-741 (MGDEVYDDVD TSDFPVSSAE MSQGTNVGKA KTEEKDLKKL KKQEKEEKDF) of Human FYB (NP_955367).

  • ポジティブ・コントロール
    • A549 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125455 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 91 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
  • 組織特異性Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.
  • 配列類似性Contains 1 SH3 domain.
  • 翻訳後修飾T-cell receptor ligation leads to increased tyrosine phosphorylation.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADAP antibody
    • Adhesion and degranulation promoting adaptor protein antibody
    • FYB 120/130 antibody
    • Fyb antibody
    • FYB-120/130 antibody
    • FYB_HUMAN antibody
    • FYN binding protein antibody
    • FYN T binding protein antibody
    • FYN-binding protein antibody
    • FYN-T-binding protein antibody
    • p120/p130 antibody
    • PRO0823 antibody
    • SLAP 130 antibody
    • SLAP-130 antibody
    • SLAP130 antibody
    • SLP 76 associated phosphoprotein antibody
    • SLP-76-associated phosphoprotein antibody
    • SLP76 associated phosphoprotein antibody
    see all

Anti-FYB antibody 画像

  • Anti-FYB antibody (ab125455) at 1 µg/ml + A549 cell lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 91 kDa

Anti-FYB antibody (ab125455) 使用論文

ab125455 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125455.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"