製品の概要

  • 製品名Anti-FXC1 antibody
    FXC1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to FXC1
  • アプリケーション適用あり: WB, ELISA, Sandwich ELISAmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 11-104 of Human FXC1 with a proprietary tag (NP_036324).

  • ポジティブ・コントロール
    • Recombinant Protein.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab118117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 12 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.
  • 組織特異性Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
  • 配列類似性Belongs to the small Tim family.
  • ドメインThe twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space. However, during the transit of FXC1/TIM10B from cytoplasm into mitochondrion, the Cys residues probably coordinate zinc, thereby preventing folding and allowing its transfer across mitochondrial outer membrane.
  • 細胞内局在Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Fracture callus 1 homolog (rat) antibody
    • Fracture callus 1 homolog antibody
    • Fracture callus protein 1 antibody
    • FxC1 antibody
    • Mitochondrial import inner membrane translocase subunit Tim10 B antibody
    • Mitochondrial import inner membrane translocase subunit Tim9 B antibody
    • OTTHUMP00000164584 antibody
    • OTTHUMP00000230720 antibody
    • TIM 10B antibody
    • Tim10b antibody
    • Tim9b antibody
    • TIM9B_HUMAN antibody
    • TIMM10B antibody
    • Translocase of inner mitochondrial membrane 10 homolog B (yeast) antibody
    see all

Anti-FXC1 antibody 画像

  • Anti-FXC1 antibody (ab118117) at 5 µg/ml + Recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 12 kDa
  • ab118117 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged FXC1 is 0.03 ng/ml.

Anti-FXC1 antibody (ab118117) 使用論文

ab118117 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab118117.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"