製品の概要

  • 製品名Anti-FUCA1 antibody
    FUCA1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FUCA1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide, corresponding to a region within internal sequence amino acids 143-192 (TNWPSPVSWN WNSKDVGPHR DLVGELGTAL RKRNIRYGLY HSLLEWFHPL) of Human FUCA1 (NP_000138).

  • ポジティブ・コントロール
    • HT1080 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
  • 関連疾患Defects in FUCA1 are the cause of fucosidosis (FUCA1D) [MIM:230000]. FUCA1D is an autosomal recessive lysosomal storage disease characterized by accumulation of fucose-containing glycolipids and glycoproteins in various tissues. Clinical signs include facial dysmorphism, dysostosis multiplex, moderate hepatomegaly, severe intellectual deficit, deafness, and according to age, angiokeratomas.
  • 配列類似性Belongs to the glycosyl hydrolase 29 family.
  • 細胞内局在Lysosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Alpha L fucosidase I antibody
    • Alpha L fucoside fucohydrolase antibody
    • Alpha-L-fucosidase 1 antibody
    • Alpha-L-fucosidase I antibody
    • Alpha-L-fucoside fucohydrolase 1 antibody
    • FUCA antibody
    • FUCA1 antibody
    • FUCO_HUMAN antibody
    • fucosidase, alpha-L, tissue antibody
    • fucosidase, alpha-L- 1, tissue antibody
    • Tissue alpha L fucosidase antibody
    • Tissue alpha-L-fucosidase antibody
    see all

Anti-FUCA1 antibody 画像

  • Anti-FUCA1 antibody (ab98310) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 54 kDa

Anti-FUCA1 antibody (ab98310) 使用論文

ab98310 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"