製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FTSJD2
  • アプリケーション
    適用あり: WB, IP, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rabbit, Guinea pig, Dog, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide mapping to a region between residues 100 and 150 of Human FTSJD2 (TrEMBL entry Q8N1G2)

  • ポジティブ・コントロール
    • Whole cell lysate from 293T cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000 - 1/25000. Detects a band of approximately 110 kDa (predicted molecular weight: 96 kDa).
IP Use at 1-5 µg/mg of lysate.
IHC-P 1/500 - 1/2000. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
  • 配列類似性
    Contains 1 G-patch domain.
    Contains 1 RrmJ-type SAM-dependent 2'-O-MTase domain.
    Contains 1 WW domain.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cap methyltransferase 1 antibody
    • Cap-specific mRNA (nucleoside-2''-O-)-methyltransferase 1 antibody
    • Cap1 2''O-ribose methyltransferase 1 antibody
    • CMTR1 antibody
    • CMTR1_HUMAN antibody
    • FLJ22156 antibody
    • FtsJ methyltransferase domain containing 2 antibody
    • FtsJ methyltransferase domain-containing protein 2 antibody
    • FTSJD 2 antibody
    • hMTr1 antibody
    • Interferon-stimulated gene 95 kDa protein antibody
    • ISG95 antibody
    • KIAA0082 antibody
    • MTr1 antibody
    • OTTHUMP00000016324 antibody
    • Uncharacterized protein KIAA0082 antibody
    see all

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma (left) and mouse CT26 colon carcinoma (right) tissues labelling FTSJD2 with ab70387 at 1/1000 (1µg/ml). Detection: DAB.
  • Detection of Human FTSJD2 by Immunoprecipitation in Whole cell lysate from 293T cells (1 mg/IP) using ab70387 at 1 µg/mg lysate for IP and at 0.1 µg/ml for subsequent WB detection.

参考文献

ab70387 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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