Anti-FSTL1/FRP 抗体 (ab71548)
Key features and details
- Rabbit polyclonal to FSTL1/FRP
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-FSTL1/FRP antibody
FSTL1/FRP 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to FSTL1/FRP -
由来種
Rabbit -
アプリケーション
適用あり: IHC-P, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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特記事項
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result, we are pleased to offer this antibody in a purified format as of 19th February 2018. The following lots is/are still unpurified and still in stock as of 19th February 2018 - GR200980-7, GR200980-9, GR200980-10. Lot numbers other than GR200980-7, GR200980-9, GR200980-10 will be purified. Please note that the dilutions may need to be adjusted accordingly. Purified antibodies have the advantage of being enriched for the fraction of immunoglobulin that specifically reacts with the target antigen and for having a reduction of serum proteins.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
Constituents: 0.92% Glycerol, 1.21% Tris, 2% Sucrose -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab71548の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
Use at an assay dependent concentration.
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WB | (1) |
Use at an assay dependent concentration.
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特記事項 |
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IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
ターゲット情報
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機能
May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin. -
組織特異性
Overexpressed in synovial tissues from rheumatoid arthritis. -
配列類似性
Contains 2 EF-hand domains.
Contains 1 follistatin-like domain.
Contains 1 Kazal-like domain.
Contains 1 VWFC domain. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 11167 Human
- Entrez Gene: 14314 Mouse
- Entrez Gene: 79210 Rat
- Omim: 605547 Human
- SwissProt: Q12841 Human
- SwissProt: Q62356 Mouse
- SwissProt: Q62632 Rat
- Unigene: 269512 Human
see all -
別名
- Anti FSTL1 antibody
- FLJ50214 antibody
- FLJ52277 antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (7)
ab71548 は 7 報の論文で使用されています。
- Liu Y et al. FSTL1 aggravates cigarette smoke-induced airway inflammation and airway remodeling by regulating autophagy. BMC Pulm Med 21:45 (2021). PubMed: 33509151
- Chen L & Liu Z Downregulation of FSTL-1 attenuates the inflammation injury during Streptococcus pneumoniae infection by inhibiting the NLRP3 and TLR4/NF-?B signaling pathway. Mol Med Rep 20:5345-5352 (2019). PubMed: 31638229
- Peng X et al. Follistatin-like protein 1 knockdown elicits human gastric cancer cell apoptosis via a STAT6-dependent pathway. Oncol Rep 42:2806-2813 (2019). PubMed: 31578589
- Zhang M et al. BMP-2 overexpression augments vascular smooth muscle cell motility by upregulating myosin Va via Erk signaling. Oxid Med Cell Longev 2014:294150 (2014). PubMed: 24790701
- Yucel G et al. State-dependent signaling by Cav1.2 regulates hair follicle stem cell function. Genes Dev 27:1217-22 (2013). PubMed: 23752588
- Gao MH et al. beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling. Cell Signal 22:584-9 (2010). PubMed: 19932173
- Liu S et al. FRP inhibits ox-LDL-induced endothelial cell apoptosis through an Akt-NF-{kappa}B-Bcl-2 pathway and inhibits endothelial cell apoptosis in an apoE-knockout mouse model. Am J Physiol Endocrinol Metab 299:E351-63 (2010). WB, IHC-P ; Mouse . PubMed: 20530739