Anti-Fructose 6 Phosphate Kinase (phospho S483) 抗体 (ab59378)

製品の概要

  • 製品名Anti-Fructose 6 Phosphate Kinase (phospho S483) antibody
    Fructose 6 Phosphate Kinase 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Fructose 6 Phosphate Kinase (phospho S483)
  • 特異性Detects endogenous levels of Fructose 6 Phosphate Kinase only when phosphorylated at serine 483.
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from Human Fructose 6 Phosphate Kinase around the phosphorylation site of serine 483 (N-Y-SP-V-G).

  • ポジティブ・コントロール
    • Human colon carcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab59378 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/40000.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • パスウェイCarbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.
  • 関連疾患Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7) [MIM:232800]; also known as Tarui disease. GSD7 is an autosomal recessive disorder characterized by exercise intolerance with associated nausea and vomiting. Short bursts of intense activity are particularly difficult. Severe muscle cramps and myoglobinuria develop after vigorous exercise. Most patients obtain a "second wind" when the onset of exercise is followed by a brief rest period. In time patients adjust their activity level and are well compensated.
  • 配列類似性Belongs to the phosphofructokinase family. Two domains subfamily.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 6 Phosphofructokinase Muscle Type antibody
    • 6-phosphofructokinase antibody
    • 6-phosphofructokinase muscle type antibody
    • EC 2.7.1.1 antibody
    • EC 2.7.1.11 antibody
    • GSD7 antibody
    • K6PF_HUMAN antibody
    • MGC8699 antibody
    • muscle type antibody
    • PFK, muscle type antibody
    • PFK-A antibody
    • PFKA antibody
    • PFKL antibody
    • PFKM antibody
    • PFKP antibody
    • PFKX antibody
    • Phosphofructo 1 Kinase Isozyme A antibody
    • Phosphofructo-1-kinase isozyme A antibody
    • Phosphofructokinase 1 antibody
    • Phosphofructokinase M antibody
    • Phosphofructokinase, muscle antibody
    • Phosphofructokinase, muscle type antibody
    • Phosphofructokinase, polypeptide X antibody
    • Phosphofructokinase-M antibody
    • Phosphohexokinase antibody
    see all

Anti-Fructose 6 Phosphate Kinase (phospho S483) antibody 画像

  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ab59378 at a 1/50-1/100 dilution.

    Left image: untreated.

    Right image: treated with phosphopeptide.

Anti-Fructose 6 Phosphate Kinase (phospho S483) antibody (ab59378) 使用論文

ab59378 has not yet been referenced specifically in any publications.

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