Anti-FPRL1 抗体 (ab63023)

製品の概要

  • 製品名Anti-FPRL1 antibody
    FPRL1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FPRL1
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to residues of the C-terminal of human FPRL1, KLH conjugated.

  • ポジティブ・コントロール
    • HL60 cells and HL60 cell extract.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab63023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/6000. Detects a band of approximately 38 kDa (predicted molecular weight: 39 kDa).
ICC/IF 1/600.

ターゲット情報

  • 機能Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
  • 組織特異性Expressed abundantly in the lung and neutrophils. Also found in the spleen and testis.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ALXR antibody
    • FMLP-R-I antibody
    • FMLP-R-II antibody
    • FMLP-related receptor I antibody
    • FMLPX antibody
    • Formyl peptide receptor 2 antibody
    • Formyl peptide receptor related antibody
    • Formyl peptide receptor-like 1 antibody
    • FPR2 antibody
    • FPR2_HUMAN antibody
    • FPR2A antibody
    • FPRH1 antibody
    • FPRH2 antibody
    • FPRL1 antibody
    • HM63 antibody
    • Lipoxin A4 receptor antibody
    • LXA4 receptor antibody
    • LXA4R antibody
    • N-formyl peptide receptor 2 antibody
    • RFP antibody
    see all

Anti-FPRL1 antibody 画像

  • Anti-FPRL1 antibody (ab63023) at 1/6000 dilution + Extracts of HL60 cells

    Predicted band size : 39 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)
  • Immunofluorescent analysis of HL60 cells using ab63023 (green) at 1:600. Nucleus have been labeled with PI (red).

Anti-FPRL1 antibody (ab63023) 使用論文

ab63023 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Mouse Tissue lysate - whole (spleen)
Loading amount 80 µg
Specification spleen
Gel Running Conditions Reduced Denaturing (10)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Xiuzhe Wang

Verified customer

投稿 Jan 21 2012

Thank you for your email.  I've looked into this, and unfortunately ab114357 would not work for blocking ab63023, as the immunogen of the antibody is amino acids 339-351, while the peptide you mentioned (ab114357) corresponds to amino acids 163-205 of ...

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Thank you for your patience while we investigated this. Unfortunately we are unable to source the blocking peptide for this antibody, so we are unable to provide a blocking peptide. I am sorry I could not be more helpful. Please do not hesitat...

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Thank you for your inquiry. We haven't tested ab63022 or ab63023 in mouse so we do not know if these antibodies will work in mouse. I've BLASTed the immunogen sequences against mouse and the results are below: Ab63022 was immunized agai...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"