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RabMAb

Anti-FOXP3 抗体 [SP97], prediluted (ab99964)

製品の概要

  • 製品名
    Anti-FOXP3 antibody [SP97], prediluted
    FOXP3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [SP97] to FOXP3, prediluted
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to C-terminus of Human FOXP3.

  • ポジティブ・コントロール
    • Human Tonsil
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab99964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1. Boil tissue section in 10mM Citrate, pH 6.0 for 10 min followed by cooling at RT for 20 min.

ターゲット情報

  • 機能
    Probable transcription factor. Plays a critical role in the control of immune response.
  • 関連疾患
    Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.
  • 配列類似性
    Contains 1 C2H2-type zinc finger.
    Contains 1 fork-head DNA-binding domain.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AIID antibody
    • DIETER antibody
    • Forkhead box P3 antibody
    • Forkhead box protein P3 antibody
    • FOXP3 antibody
    • FOXP3_HUMAN antibody
    • FOXP3delta7 antibody
    • Immune dysregulation polyendocrinopathy enteropathy X linked antibody
    • Immunodeficiency polyendocrinopathy enteropathy X linked antibody
    • IPEX antibody
    • JM2 antibody
    • MGC141961 antibody
    • MGC141963 antibody
    • OTTHUMP00000025832 antibody
    • OTTHUMP00000025833 antibody
    • OTTHUMP00000226737 antibody
    • PIDX antibody
    • Scurfin antibody
    • XPID antibody
    see all

画像

  • Staining of Human FOXP3 in a Formalin/PFA-fixed paraffin-embedded section of Human Tonsil using prediluted ab99964.

プロトコール

参考文献

This product has been referenced in:
  • Märkl B  et al. The role of lymph node size and FOXP3+ regulatory T cells in node-negative colon cancer. J Clin Pathol 70:443-447 (2017). Read more (PubMed: 27879345) »
  • Stenström B  et al. Helicobacter pylori overcomes natural immunity in repeated infections. Clin Case Rep 4:1026-1033 (2016). Read more (PubMed: 27830066) »

See all 4 Publications for this product

レビューと Q&A

Many of our pre-diluted products, such as ab99964, are colored – this is so that we and our customers can quickly identify these as pre-diluted (rather than concentrated) Ab formulations.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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