製品の概要

  • 製品名Anti-FOXP1 antibody
    FOXP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FOXP1
  • アプリケーション適用あり: IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Cow, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant
  • 免疫原

    Synthetic peptide from a region within amino acids 250-300 of Human FOXP1 (NP_116071.2)

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab93776 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP Use at 2-5 µg/mg of lysate.

ターゲット情報

  • 機能Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development.
  • 関連疾患Note=A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. Translocation t(9;3)(p13;p14.1) with PAX5.
    Defects in FOXP1 are the cause of mental retardation with language impairment and autistic features (MRLIAF) [MIM:613670]. It is a developmental disorder characterized by mild to moderate mental retardation, language impairment, and autistic features. Patients show global delay, delayed walking, severely delayed speech development, and behavioral abnormalities, including irritability, hyperactivity, aggression, and stereotypical rigid behaviors.
  • 配列類似性Contains 1 C2H2-type zinc finger.
    Contains 1 fork-head DNA-binding domain.
  • ドメインThe leucine-zipper is required for dimerization and transcriptional repression.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 12CC4 antibody
    • FLJ23741 antibody
    • Fork head related protein like B antibody
    • Forkhead box P1 antibody
    • Forkhead box protein P1 antibody
    • FOX P1 antibody
    • FOXP 1 antibody
    • foxp1 antibody
    • FOXP1_HUMAN antibody
    • Glutamine rich factor 1 antibody
    • hFKH1B antibody
    • HSPC215 antibody
    • MGC12942 antibody
    • MGC88572 antibody
    • MGC99551 antibody
    • QRF 1 antibody
    • QRF1 antibody
    see all

Anti-FOXP1 antibody 画像

  • 1 mg HeLa whole cell lysate was immunoprecipitated with 3 µg/mg ab93776. 20% of the immunoprecipitate was used for Western blotting and ab93776 was used at 1 µg/ml followed by a chemiluminescence exposure of 10 seconds to reveal the protein bands.

Anti-FOXP1 antibody (ab93776) 使用論文

ab93776 has not yet been referenced specifically in any publications.

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