製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57216 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1 - 5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development.
    • 関連疾患Note=A chromosomal aberration involving FOXP1 is found in acute lymphoblastic leukemia. Translocation t(9;3)(p13;p14.1) with PAX5.
      Defects in FOXP1 are the cause of mental retardation with language impairment and autistic features (MRLIAF) [MIM:613670]. It is a developmental disorder characterized by mild to moderate mental retardation, language impairment, and autistic features. Patients show global delay, delayed walking, severely delayed speech development, and behavioral abnormalities, including irritability, hyperactivity, aggression, and stereotypical rigid behaviors.
    • 配列類似性Contains 1 C2H2-type zinc finger.
      Contains 1 fork-head DNA-binding domain.
    • ドメインThe leucine-zipper is required for dimerization and transcriptional repression.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 12CC4 antibody
      • FLJ23741 antibody
      • Fork head related protein like B antibody
      • Forkhead box P1 antibody
      • Forkhead box protein P1 antibody
      • FOX P1 antibody
      • FOXP 1 antibody
      • foxp1 antibody
      • FOXP1_HUMAN antibody
      • Glutamine rich factor 1 antibody
      • hFKH1B antibody
      • HSPC215 antibody
      • MGC12942 antibody
      • MGC88572 antibody
      • MGC99551 antibody
      • QRF 1 antibody
      • QRF1 antibody
      see all

    Anti-FOXP1 antibody 画像

    Anti-FOXP1 antibody (ab57216) 使用論文

    ab57216 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57216.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"