Anti-FOXN4 抗体 (ab98860)

製品の概要

  • 製品名Anti-FOXN4 antibody
    FOXN4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FOXN4
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 431-480 of Human FOXN4 (NP_998761).

  • ポジティブ・コントロール
    • OVCAR-3 cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab98860 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.
  • 配列類似性Contains 1 fork-head DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ35967 antibody
    • Forkhead box N4 antibody
    • Forkhead box protein N4 antibody
    • Forkhead/winged helix transcription factor FOXN4 antibody
    • FOXN4 antibody
    • FOXN4_HUMAN antibody
    see all

Anti-FOXN4 antibody 画像

  • Anti-FOXN4 antibody (ab98860) at 1 µg/ml + OVCAR-3 cell lysate at 10 µg
    Developed using the ECL technique

    Predicted band size : 55 kDa

Anti-FOXN4 antibody (ab98860) 使用論文

ab98860 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (retina)
Specification retina
Fixative formalin
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate ph 6
Permeabilization Yes - triton and tween
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投稿 Jun 20 2012

DISCOUNT CODE: xx
Expiration date: 14. Juin 2012
I am very pleased to hear you would like to accept our offer and test ab98860 in IHC-P. This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please ...

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Thank you very much for your interest in ab98860.
To our knowledge, ab98860 has not been tested in immunohistochemistry on paraffin sections (IHC-P). We do not have any indications whether it is suitable or not for IHC-P. If you would like to test...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"