Anti-FOXM1 抗体 [263C2a] (ab58675)

製品の概要

• 製品名
  Anti-FOXM1 antibody [263C2a]
  FOXM1 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [263C2a] to FOXM1
• アプリケーション
  適用あり: WB, Dot blotmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Recombinant fragment (Human)

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
• バッファー
  Preservative: 0.05% Sodium Azide
  Constituents: 1% BSA, PBS (8.0mM Sodium phosphate, 3.0mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate), pH 7.4
• Concentration information loading...
• 精製度
  Protein G purified
• 特記事項（精製）
  Purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane.
• ポリ/モノ
  モノクローナル
• クローン名
  263C2a
• アイソタイプ
  IgG1
• 研究分野
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • Forkhead Box

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • Forkhead Box
  • Other FOXes

  • Cancer
  • Oncoproteins/suppressors
  • Oncoproteins
  • Transcription factors

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 機能
  Transcriptional activatory factor. May play a role in the control of cell proliferation.
• 組織特異性
  Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
• 配列類似性
  Contains 1 fork-head DNA-binding domain.
• 発生段階
  Embryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.
• ドメイン
  Within the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.
• 翻訳後修飾
  Phosphorylated in M (mitotic) phase.
• 細胞内局在
  Nucleus.

• Target information above from: UniProt accession Q08050 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 2305 Human
  • Omim: 602341 Human
  • SwissProt: Q08050 Human
  • Unigene: 239 Human
• 別名
  • FKHL16 antibody
  • Forkhead box M1 antibody
  • Forkhead box protein M1 antibody

  • forkhead like 16 antibody
  • Forkhead-related protein FKHL16 antibody
  • FOX M1 antibody
  • Foxm1 antibody
  • FOXM1_HUMAN antibody
  • FOXM1B antibody
  • Hepatocyte nuclear factor 3 forkhead homolog 11 antibody
  • HFH-11 antibody
  • HFH11 antibody
  • HNF-3/fork-head homolog 11 antibody
  • HNF3 antibody
  • INS1 antibody
  • M phase phosphoprotein 2 antibody
  • M-phase phosphoprotein 2 antibody
  • MPHOSPH2 antibody
  • MPM-2 reactive phosphoprotein 2 antibody
  • MPP2 antibody
  • PIG29 antibody
  • TGT3 antibody
  • Transcription factor Trident antibody
  • Trident antibody
  • WIN antibody
  • Winged-helix factor from INS-1 cells antibody
  • Winged-helix factor from INS1 cells antibody

  see all

プロトコール

• Western blot protocols