製品の概要

  • 製品名Anti-FOXG1 antibody
    FOXG1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to FOXG1
  • 特異性This antibody will recognise both human FOXG1A and FOXG1B, which are almost completely identical.
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Human, Xenopus laevis
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide corresponding to Human FOXG1 aa 457-469 (C terminal).
    Sequence:

    C-HQNQGSSSNPLIH


    Database link: P55316
    (Peptide available as ab22945)

  • ポジティブ・コントロール
    • Human Brain lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab3394 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/500. PubMed: 17435750
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 54 kDa).Can be blocked with Human FOXG1 peptide (ab22945). The additonal unknown band at 70kDa was successfully blocked with the immunising peptide.

ターゲット情報

  • 機能Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
  • 組織特異性Expression is restricted to the neurons of the developing telencephalon.
  • 関連疾患Defects in FOXG1 are the cause of congenital variant of Rett syndrome (RTTCV) [MIM:613454]. RTTCV is a severe neurodevelopmental disorder with features of classic Rett syndrome but earlier onset in the first months of life. Clinical features include progressive microcephaly, hypotonia, irresponsiveness and irritability in the neonatal period, mental retardation, psychomotor regression and stereotypical movements.
  • 配列類似性Contains 1 fork-head DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BF-1 antibody
    • BF-2 antibody
    • BF1 antibody
    • BF2 antibody
    • Brain factor 1 antibody
    • Brain factor 2 antibody
    • FHKL antibody
    • FKH2 antibody
    • FKHL1 antibody
    • FKHL2 antibody
    • FKHL3 antibody
    • FKHL4 antibody
    • Forkhead box protein G1 antibody
    • Forkhead box protein G1A antibody
    • Forkhead box protein G1B antibody
    • Forkhead box protein G1C antibody
    • Forkhead like 1 antibody
    • Forkhead like 2 antibody
    • Forkhead like 3 antibody
    • Forkhead like 4 antibody
    • Forkhead-related protein FKHL1 antibody
    • Forkhead-related protein FKHL2 antibody
    • Forkhead-related protein FKHL3 antibody
    • FOXG1 antibody
    • FOXG1_HUMAN antibody
    • FOXG1A antibody
    • FOXG1B antibody
    • FOXG1C antibody
    • HBF 1 antibody
    • HBF G2 antibody
    • hBF-2 antibody
    • HBF2 antibody
    • HFK1 antibody
    • HFK2 antibody
    • HFK3 antibody
    • KHL2 antibody
    • Oncogene QIN antibody
    • QIN antibody
    see all

Anti-FOXG1 antibody 画像



  • Predicted band size : 54 kDa
    ab3394 staining (2µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. ab3394 (0.3 µg/ml) staining of Human Brain lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-FOXG1 antibody (ab3394) 使用論文

This product has been referenced in:
  • Li JV  et al. Transcriptional repression of AIB1 by FoxG1 leads to apoptosis in breast cancer cells. Mol Endocrinol 27:1113-27 (2013). Read more (PubMed: 23660594) »
  • Regad T  et al. The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF. Nat Cell Biol 9:531-40 (2007). ICC/IF ; Mouse . Read more (PubMed: 17435750) »

See all 2 Publications for this product

Product Wall

I have issued a free of charge replacement for ab18259, with the order number *****. The replacement is ab3394. To check the status of the order please contact our Customer Service team and reference this number. I suggested in my conve...

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Thanks for contacting us and letting us know about the problems with ab3394. I am sending a free of charge vial of ab18259 on the order ***, which should arrive shortly. Please keep me updated on the results using this replacement, and let me k...

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Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (brain)
Specification brain
Fixative Paraformaldehyde
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10%
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Abcam user community

Verified customer

投稿 Oct 11 2005

Thank you very much for your enquiry. To our knowledge, this antibody has yet to be tested in IHC. All tested applications are specified on Abcam product datasheets. If you decide to go ahead and purchase this product, please let us know how you get on...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"