製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FOLR2
  • アプリケーション
    適用あり: Flow Cyt, WB, ELISAmore details
  • 種交差性
    交差種: Human, Recombinant fragment
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide corresponding to N terminal residues of human FOLR2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use at an assay dependent concentration. PubMed: 23439585ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB Use at an assay dependent concentration. Predicted molecular weight: 29 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
  • 組織特異性
    Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
  • 配列類似性
    Belongs to the folate receptor family.
  • 翻訳後修飾
    Eight disulfide bonds are present.
    N-glycosylated.
  • 細胞内局在
    Cell membrane. Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • beta hFR antibody
    • FBP antibody
    • FBP/PL 1 antibody
    • FBP2 antibody
    • fetal/placental antibody
    • folate receptor 2 (fetal) antibody
    • Folate receptor 2 antibody
    • Folate receptor antibody
    • Folate receptor beta antibody
    • Folate receptor, fetal/placental antibody
    • Folbp 2 antibody
    • Folbp2 antibody
    • Folr2 antibody
    • FOLR2_HUMAN antibody
    • FR beta antibody
    • FR P3 antibody
    • FR-beta antibody
    • Placental folate binding protein antibody
    • Placental folate-binding protein antibody
    see all

Anti-FOLR2 antibody (ab56067) 使用論文

This product has been referenced in:
  • Perna AF  et al. Altered folate receptor 2 expression in uraemic patients on haemodialysis: implications for folate resistance. Nephrol Dial Transplant N/A:N/A (2013). WB, Flow Cyt ; Human . Read more (PubMed: 23439585) »
  • Stronach EA  et al. HDAC4-regulated STAT1 activation mediates platinum resistance in ovarian cancer. Cancer Res 71:4412-22 (2011). WB ; Human . Read more (PubMed: 21571862) »

See all 2 Publications for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (THP-1)
Specification
THP-1
Fixative
Paraformaldehyde
Permeabilization
No
Blocking step
Protein Block (serum free) as blocking agent for 20 minute(s) · Concentration: 100% · Temperature: 4°C
Username

Mr. Alan Maziarz

Verified customer

投稿 Oct 14 2008

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録