Anti-FNDC3A 抗体 (ab71577)

製品の概要

• 製品名
  Anti-FNDC3A antibody
• 製品の詳細
  Rabbit polyclonal to FNDC3A
• アプリケーション
  適用あり: WB, IHC-Pmore details
• 種交差性
  交差種: Human
  交差が予測される動物種: Mouse
• 免疫原

  Synthetic peptide derived from the C terminal domain of human FNDC3A

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファー
  Preservative: None
  Constituents: Whole serum
• 精製度
  Whole antiserum
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Tags & Cell Markers
  • Cell Type Markers
  • Other Cell Types

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 関連性
  FNDC3A is a member of a three-gene family in mice. It is expressed in several tissues including testis, and encodes a novel protein composed of a proline-rich amino-terminus, nine fibronectin type-III domains, and a hydrophobic carboxy-terminus. The proline-rich region of each family member contains conserved amino acids that include a PPGY consensus binding site for type I WW domain containing proteins. The hydrophobic carboxy-terminus is similar to that found in 'tail-anchored' proteins, integral membrane proteins that are localized to the cytosolic face of the endoplasmic reticulum. Immunohistochemical staining has shown that FNDC3A localizes to the acrosome of spermatids, as well as to Leydig cells in the mouse testis. FNDC3A may be involved in mediating spermatid-Sertoli adhesion during mouse spermatogenesis and mutation of FNDC3A is the cause of male sterility in sys mice. FNDC3A has also been found to be overexpressed in human odontoblasts.
• 参照データベース
  • Entrez Gene: 22862 Human
  • SwissProt: Q9Y2H6 Human
• 別名
  • Fibronectin type III domain containing protein 3a antibody
  • FNDC3 antibody
  • HUGO antibody
  • KIAA0970 antibody

プロトコール

• Western blot protocols
• Immunohistochemistry protocols