製品の概要

  • 製品名Anti-FMO3 antibody
    FMO3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FMO3
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee
  • 免疫原

    Synthetic peptide derived from Human FMO3

  • ポジティブ・コントロール
    • Jurkat cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab62178 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 60 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

Titre using peptide based assay: 1/1562500.

ターゲット情報

  • 機能Involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. Plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.
  • 組織特異性Liver.
  • 関連疾患Defects in FMO3 are the cause of trimethylaminuria (TMAU) [MIM:602079]; also known as fish-odor syndrome. TMAU is an inborn error of metabolism associated with an offensive body odor and caused by deficiency of FMO-mediated N-oxidation of amino-trimethylamine (TMA) derived from foodstuffs. Such individuals excrete relatively large amounts of TMA in their urine, sweat, and breath, and exhibit a fishy body odor characteristic of the malodorous free amine.
  • 配列類似性Belongs to the FMO family.
  • 細胞内局在Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Dimethylaniline monooxygenase [N oxide forming] 3 antibody
    • Dimethylaniline monooxygenase [N-oxide-forming] 3 antibody
    • Dimethylaniline monooxygenase 3 antibody
    • Dimethylaniline oxidase 3 antibody
    • dJ127D3.1 antibody
    • Flavin containing monooxygenase 3 antibody
    • FMO 3 antibody
    • FMO form 2 antibody
    • FMO II antibody
    • FMO3 antibody
    • FMO3_HUMAN antibody
    • FMOII antibody
    • Hepatic flavin containing monooxygenase 3 antibody
    • Hepatic flavin-containing monooxygenase 3 antibody
    • MGC34400 antibody
    • TMAU antibody
    • Trimethylamine monooxygenase antibody
    see all

Anti-FMO3 antibody 画像

  • All lanes : Anti-FMO3 antibody (ab62178) at 0.5 µg/ml (in 5% skim milk / PBS buffer)

    Lane 1 : Molecular weight marker
    Lane 2 : Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 60 kDa
    Observed band size : 58 kDa (why is the actual band size different from the predicted?)

Anti-FMO3 antibody (ab62178) 使用論文

ab62178 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"