製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FLJ39378
  • アプリケーション
    適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    17 amino acid synthetic peptide derived from near the N terminal of Human FLJ39378 (AAH89444).

  • ポジティブ・コントロール
    • Rat cerebellum tissue lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab117441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.

ターゲット情報

  • 機能
    Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
  • 組織特異性
    Widely expressed. Expressed at lower level in liver and kidney.
  • 配列類似性
    Belongs to the RILPL family.
    Contains 1 RILP-like domain.
  • 翻訳後修飾
    S-nitrosylation is required for the interaction with GAPDH.
  • 細胞内局在
    Cytoplasm > cytosol.
  • Information by UniProt
  • 参照データベース
  • 別名
    • GOSPEL antibody
    • MGC105128 antibody
    • MGC99793 antibody
    • Rab interacting lysosomal protein like 1 antibody
    • Rab-interacting lysosomal-like protein 1 antibody
    • RILP like protein 1 antibody
    • RILP-like protein 1 antibody
    • RILPL 1 antibody
    • rilpl1 antibody
    • RIPL1_HUMAN antibody
    • RLP1 antibody
    see all

Anti-FLJ39378 antibody 画像

  • Lane 1 : Anti-FLJ39378 antibody (ab117441) at 0.5 µg/ml
    Lane 2 : Anti-FLJ39378 antibody (ab117441) at 1 µg/ml

    Lane 1 : Rat cerebellum tissue lysate
    Lane 2 : Rat cerebellum tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 47 kDa
  • Immunofluorescence analysis of mouse brain cells, staining FLJ39378 with ab117441 at 20 µg/ml.

Anti-FLJ39378 antibody (ab117441) 使用論文

ab117441 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab117441.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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