The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 20 µg/ml.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 47 kDa.
機能Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH (By similarity). Does not regulate lysosomal morphology and distribution.
組織特異性Widely expressed. Expressed at lower level in liver and kidney.
配列類似性Belongs to the RILPL family. Contains 1 RILP-like domain.
翻訳後修飾S-nitrosylation is required for the interaction with GAPDH.