製品の概要

  • 製品名
    Flecainide
  • 製品の詳細
    Sodium channel blocker
  • 生理活性の詳細
    Sodium channel blocker. Class IC antiarrhythmic agent. Inhibits fast Na+ current in cardiac muscle in a use- and concentration-dependent manner. Also inhibits cardiac ryanodine receptors. Orally-active.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Hilliard FA  et al. Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass. J Mol Cell Cardiol 48:293-301 (2010). Read more (PubMed: 19835880) »
  • Rouet R & Ducouret P Use- and concentration-dependent effects of flecainide in guinea pig right ventricular muscle. J Cardiovasc Pharmacol 24:177-83 (1994). Read more (PubMed: 7526048) »
  • Singh BN  et al. The electrophysiology and pharmacology of verapamil, flecainide, and amiodarone: correlations with clinical effects and antiarrhythmic actions. Ann N Y Acad Sci 432:210-35 (1984). Read more (PubMed: 6395762) »

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