製品の概要

  • 製品名Anti-FKBP51 antibody
    FKBP51 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FKBP51
  • アプリケーション適用あり: WB, IP, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Hamster, Dog, Human, Xenopus laevis, Non Human Primates
  • 免疫原

    Synthetic peptide corresponding to Human FKBP51 aa 394-407.
    Sequence:

    CQKKAKEHNERDRR


    (Peptide available as ab4924)

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab2901 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 51 kDa.Can be blocked with FKBP51 peptide (ab4924). By Western blot, this antibody detects an ~51 kDa protein representing FKBP 51 in HeLa cell lysate. By Western blot this antibody also detects FKBP 51 in whole tissue extracts from rat kidney and rat and mouse testes.
IP Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration. PubMed: 20422297

ターゲット情報

  • 機能Interacts with functionally mature heterooligomeric progesterone receptor complexes along with HSP90 and TEBP.
  • 組織特異性Widely expressed, enriched in testis compared to other tissues.
  • 配列類似性Contains 2 PPIase FKBP-type domains.
    Contains 3 TPR repeats.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 51 kDa FK506 binding protein 5 antibody
    • 51 kDa FK506 binding protein antibody
    • 51 kDa FK506-binding protein antibody
    • 51 kDa FKBP antibody
    • 54 kDa progesterone receptor associated immunophilin antibody
    • 54 kDa progesterone receptor-associated immunophilin antibody
    • AIG 6 antibody
    • AIG6 antibody
    • Androgen regulated protein 6 antibody
    • Androgen-regulated protein 6 antibody
    • FF1 antigen antibody
    • FK506 binding protein 5 antibody
    • FK506-binding protein 5 antibody
    • FKBP 5 antibody
    • FKBP 51 antibody
    • FKBP 54 antibody
    • FKBP-5 antibody
    • FKBP-51 antibody
    • FKBP5 antibody
    • FKBP5_HUMAN antibody
    • FKBP54 antibody
    • HSP90 binding immunophilin antibody
    • HSP90-binding immunophilin antibody
    • MGC111006 antibody
    • OTTHUMP00000016268 antibody
    • P54 antibody
    • Peptidyl prolyl cis trans isomerase antibody
    • Peptidyl-prolyl cis-trans isomerase FKBP5 antibody
    • Peptidylprolyl cis trans isomerase antibody
    • PPIase antibody
    • PPIase FKBP5 antibody
    • Ptg 10 antibody
    • Ptg10 antibody
    • Rotamase antibody
    • T cell FK506 binding protein antibody
    see all

Anti-FKBP51 antibody 画像

  • Western blot of FKBP51 on HeLa cell lysate using ab2901.

Anti-FKBP51 antibody (ab2901) 使用論文

This product has been referenced in:
  • Allan AM  et al. Prenatal alcohol exposure modifies glucocorticoid receptor subcellular distribution in the medial prefrontal cortex and impairs frontal cortex-dependent learning. PLoS One 9:e96200 (2014). WB ; Mouse . Read more (PubMed: 24755652) »
  • Hadamitzky M  et al. Acute systemic rapamycin induces neurobehavioral alterations in rats. Behav Brain Res 273:16-22 (2014). Read more (PubMed: 25043732) »

See all 7 Publications for this product

Product Wall

Merci pour votre enquête.

A ma connaissance, il n'existent pas des isoformes décrites de FKBP51. Il existent par contre des sites de phosphorylation. Un doublet de la bande autour de 50kD pourrait donc être du à phos...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Mouse Tissue lysate - whole (Brain Tissue)
Loading amount 40 µg
Specification Brain Tissue
Gel Running Conditions Non-reduced Denaturing (10% Bis-Tris)
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C
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Abcam user community

Verified customer

投稿 May 27 2011

Thank you for your enquiry. We did a BLAST search on the immunizing sequence and the only FKBP that came up was 51. We do not think this is 12 but it may be a degraded fragment from 51.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"