FJX1 is the human ortholog of mouse and Drosophila four-jointed gene product. The Drosophila protein is important for growth and differentiation of legs and wings, and for proper development of the eyes. The exact function of this gene in humans is not known.
Putative secreted ligand homologous to FJX1 antibody
Immunocytochemistry/ Immunofluorescence - Anti-FJX1 antibody (ab80264)Image from Al-Greene NT et al., PLoS One. 2013;8(7):e69660. Fig 3.; doi: 10.1371/journal.pone.0069660.
ab80264 staining FJX1 by ICC/IF (Immunocytochemistry/immunofluorescence) in HEK293T cells stably expressing MYC-tagged FJX1 dual stained for FJX1 (i, green) and MYC (ii, red) or FJX1 (iv, green) and the Golgi marker, GM130 (v, red). Nuclei were stained with 4',6-diamidino-2-phenylindole (blue). Respective merged images are shown (iii, vi). Scale bar = 100 μm
Cells were fixed with 4% paraformaldehyde, blocked with 3% BSA and incubated with primary antibody and an Alexa Fluor® was used as the secondary antibody.
Al-Greene NT et al. Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma. PLoS One8:e69660 (2013).
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