製品の概要

  • 製品名Anti-FIP1L1 antibody
    FIP1L1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FIP1L1
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Cow, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to a region within amino acids 544 - 594 of Human FIP1L1 (NP_112179.2)

  • ポジティブ・コントロール
    • Anaplastic thyroid carcinoma, bladder cell carcinoma, breast carcinoma, colon carcinoma, Hodgkin's lymphoma, linitis plastica stomach cancer, lung adenocarcinoma, ovarian carcinoma, pancreatic islet cell tumor, prostate carcinoma, skin basal cell carcinoma, skin squamous cell carcinoma, small cell lung Cancer, stomach adenocarcinoma, skin cancer.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500. Antigen retrieval with citrate buffer may enhance staining.
    Note: expected to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性FIP1L1 is an integral subunit of the cleavage and polyadenylation specificity factor (CPSF) complex. CPSF is a multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA and interacts with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 binds to U-rich RNA sequence elements surrounding the poly(A) site and contributes to poly(A) site recognition and stimulates poly(A) addition. FIP1L1 may act to tether poly(A) polymerase to the CPSF complex. A fusion of FIP1L1 and PDGFRA (FIP1L1-PDGFRA) is a recurrent molecular lesion in eosinophilia-associated myeloproliferative disorders.
    • 細胞内局在Nuclear
    • 参照データベース
    • 別名
      • DKFZp586K0717 antibody
      • Factor interacting with PAP antibody
      • FIP1 antibody
      • FIP1 like 1 (S cerevisiae) antibody
      • FIP1 like 1 antibody
      • FLJ33619 antibody
      • hFip 1 antibody
      • hFip1 antibody
      • Pre mRNA 3 end processing factor FIP1 antibody
      • Rearranged in hypereosinophilia antibody
      • RHE antibody
      see all

    Anti-FIP1L1 antibody 画像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human pancreatic islet cell tumor, using 1/100 ab84670 followed by DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human skin cancer, using 1/100 ab84670 followed by DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Humanbreast carcinoma, using 1/100 ab84670 in conjunction with 1/100 Goat anti-Rabbit IgG conjugated with a fluorescent dye (red).

    Anti-FIP1L1 antibody (ab84670) 使用論文

    ab84670 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab84670.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"