製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FILIP1L
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    antigen sequence: DNEPPDYKSL IPLERAVING QLYEESENQD EDPNDEGSVL SFKCSQSTPC PVNRKLWIPW MKSKEGHLQN GKMQTKPNAN FVQPGDLVLS HTPGQP, corresponding to internal sequence amino acids 806-901 of Human FILIP1L.

  • ポジティブ・コントロール
    • Human colon tissue; RT 4, U 251 MG, Liver and Tonsil lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab122835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

ターゲット情報

  • 機能
    Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
  • 組織特異性
    Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. Down-regulated in ovarian cancer.
  • 配列類似性
    Belongs to the FILIP1 family.
  • 細胞内局在
    Cytoplasm. Membrane. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 130 kDa GPBP-interacting protein antibody
    • 90 kDa GPBP-interacting protein antibody
    • COL4A3BPIP antibody
    • DOC-1 antibody
    • DOC1 antibody
    • Downregulated in ovarian cancer 1 81 kDa isoform antibody
    • FIL1L_HUMAN antibody
    • Filamin A-interacting protein 1-like antibody
    • FILIP1L antibody
    • GIP130 antibody
    • GIP130a antibody
    • GIP130b antibody
    • GIP130c antibody
    • GIP90 antibody
    • GPBP interacting protein 90 antibody
    • Protein down-regulated in ovarian cancer 1 antibody
    see all

画像

  • All lanes : Anti-FILIP1L antibody (ab122835) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique
  • ab122835 at 1/200 dilution staining FILIP1L in Paraffin-embedded Human colon tissue by Immunohistochemistry.

参考文献

ab122835 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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