Anti-Fibrinopeptide B 抗体 - C-terminal (ab86572)


  • 製品名
    Anti-Fibrinopeptide B antibody - C-terminal
    Fibrinopeptide B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Fibrinopeptide B - C-terminal
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide derived from the C-terminal region of Human Fibrinopeptide B, conjugated to KLH

  • ポジティブ・コントロール
    • Mouse liver tissue lysate


  • 製品の状態
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Ammonium Sulphate Precipitation
  • ポリ/モノ
  • アイソタイプ
  • 研究分野


Our Abpromise guarantee covers the use of ab86572 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Predicted molecular weight: 56 kDa.
ELISA 1/1000.


  • 機能
    Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
  • 関連疾患
    Defects in FGB are a cause of thrombophilia.
    Defects in FGB are a cause of congenital afibrinogenemia (CAFBN) [MIM:202400]. This rare autosomal recessive disorder is characterized by bleeding that varies from mild to severe and by complete absence or extremely low levels of plasma and platelet fibrinogen.
  • 配列類似性
    Contains 1 fibrinogen C-terminal domain.
  • ドメイン
    A long coiled coil structure formed by 3 polypeptide chains connects the central nodule to the C-terminal domains (distal nodules). The long C-terminal ends of the alpha chains fold back, contributing a fourth strand to the coiled coil structure.
  • 翻訳後修飾
    Conversion of fibrinogen to fibrin is triggered by thrombin, which cleaves fibrinopeptides A and B from alpha and beta chains, and thus exposes the N-terminal polymerization sites responsible for the formation of the soft clot. The soft clot is converted into the hard clot by factor XIIIA which catalyzes the epsilon-(gamma-glutamyl)lysine cross-linking between gamma chains (stronger) and between alpha chains (weaker) of different monomers.
  • 細胞内局在
  • Information by UniProt
  • 参照データベース
  • 別名
    • Epididymis secretory sperm binding protein Li 78p antibody
    • FGB antibody
    • FIBB_HUMAN antibody
    • Fibrinogen B beta polypeptide antibody
    • Fibrinogen beta chain antibody
    • Fibrinogen beta polypeptide chain antibody
    • Fibrinopeptide B antibody
    • HEL S 78p antibody
    • Liver regeneration-related protein LRRG036/LRRG043/LRRG189 antibody
    • MGC104327 antibody
    • MGC120405 antibody
    • OTTHUMP00000197066 antibody
    see all

Anti-Fibrinopeptide B antibody - C-terminal 画像

  • Anti-Fibrinopeptide B antibody - C-terminal (ab86572) at 1/50 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 56 kDa


Anti-Fibrinopeptide B antibody - C-terminal (ab86572) 使用論文

ab86572 has not yet been referenced specifically in any publications.

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There are 2 antibodies involved in this experiment ab10066 and ab86572; in sELISA it will be difficult to know which antibody is failing so my suggestion would be trying, either the Indirect ELISA (by coating antigen)...

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