Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 127 kDa.
Use a concentration of 13 µg/ml.
Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
Ubiquitous. Highly expressed in spleen.
Belongs to the formin homology family.
Contains 1 FH1 (formin homology 1) domain. Contains 1 FH2 (formin homology 2) domain. Contains 1 GBD/FH3 (Rho GTPase-binding/formin homology 3) domain.
Regulated by intramolecular binding to a C-terminal auto-inhibitory domain. Effector binding abolishes this interaction and activates the protein.
Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic.
Information by UniProt
FH1/FH2 domain containing protein antibody
FH1/FH2 domain containing protein 1 antibody
FH1/FH2 domain-containing protein 1 antibody
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