製品の概要

  • 製品名Anti-FH antibody
    FH 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FH
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 89 and 335 of FH

  • ポジティブ・コントロール
    • 293T and A431 whole cell lysates OVCAR3 xenograft tissue

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab95950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 55 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Also acts as a tumor suppressor.
  • パスウェイCarbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.
  • 関連疾患Defects in FH are the cause of fumarase deficiency (FHD) [MIM:606812]; also known as fumaricaciduria. FHD is characterized by progressive encephalopathy, developmental delay, hypotonia, cerebral atrophy and lactic and pyruvic acidemia.
    Defects in FH are the cause of multiple cutaneous and uterine leiomyomata (MCUL1) [MIM:150800]. MCUL1 is an autosomal dominant condition in which affected individuals develop benign smooth muscle tumors (leiomyomata) of the skin. Affected females also usually develop leiomyomata of the uterus (fibroids).
    Defects in FH are the cause of hereditary leiomyomatosis and renal cell cancer (HLRCC) [MIM:605839].
  • 配列類似性Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  • 細胞内局在Cytoplasm and Mitochondrion.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FH antibody
    • Fumarase antibody
    • Fumarate hydratase antibody
    • Fumarate hydratase mitochondrial antibody
    • Fumarate hydratase, mitochondrial antibody
    • FUMH_HUMAN antibody
    • HLRCC antibody
    • LRCC antibody
    • MCL antibody
    • MCUL 1 antibody
    • MCUL1 antibody
    • MS709 antibody
    • Multiple hereditary cutaneous leiomyomata antibody
    see all

Anti-FH antibody 画像

  • All lanes : Anti-FH antibody (ab95950) at 1/5000 dilution

    Lane 1 : 293T whole cell lysate
    Lane 2 : A431 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 55 kDa
  • ab95950 at a 1:500 dilution, staining human FH in OVCAR3 xenograft, using Immunohistochemistry, Formalin/PFA-fixed paraffin-embedded tissue.

Anti-FH antibody (ab95950) 使用論文

ab95950 has not yet been referenced specifically in any publications.

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