製品の概要

  • 製品名Anti-FGFR1 alpha antibody [M1C4]
    FGFR1 alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [M1C4] to FGFR1 alpha
  • 特異性Reacts with alpha isoform of FRFR1.
  • アプリケーション適用あり: IP, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant human ectodomain of FGFr1a expressed in E. coli beginning with pro23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.

  • エピトープCOOH-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu75 and ser119 of FGFr1a. Epitope is masked in undenatured FGFr1a.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab830 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
WB
  • 追加情報Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1.
    Immunoprecipitation: Ig loop I fragment of denatured, intact FGFr1a.
    Immunohistochemistry: untested; predicted to be poor due to masked epitope.
  • ターゲット情報

    • 関連性FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family and contains an Ig-like domain and a tyrosine kinase domain. This receptor has multiple isoforms and is a Type I membrane protein. FGFR1 is widely expressed, with distinct isoforms expressed in specific tissues. FGFR1 binds fibroblast growth factor and induces mitogenesis and cellular differentiation. Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis. FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform. FGFR1 has been shown to interact with N-cadherin and NCAM.
    • 細胞内局在Cell Membrane
    • 参照データベース
    • 別名
      • BFGFR antibody
      • CD331 antibody
      • CEK antibody
      • FGFBR antibody
      • FGFR1 antibody
      • FLG antibody
      • FLT2 antibody
      • FMS like tyrosine kinase 2 antibody
      • HBGFR antibody
      • KAL2 antibody
      • N SAM antibody
      • OGD antibody
      see all

    Anti-FGFR1 alpha antibody [M1C4] (ab830) 使用論文

    ab830 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"