製品の概要

  • 製品名Anti-FGF10 antibody
    FGF10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FGF10
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Sheep, Non Human Primates
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human FGF10.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Human lung tissue lysate and A549 whole cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab91024 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 23 kDa).

ターゲット情報

  • 機能Could be a growth factor active in the process of wound healing. Acts as a mitogen in the lung. May act in a manner similar to FGF-7.
  • 関連疾患Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG) [MIM:180920]. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.
    Defects in FGF10 are a cause of lacrimo-auriculo-dento-digital syndrome (LADDS) [MIM:149730]; also known as Levy-Hollister syndrome. LADDS is a form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. LADDS is an autosomal dominant syndrome characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed.
  • 配列類似性Belongs to the heparin-binding growth factors family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BB213776 antibody
    • fd11d03 antibody
    • FGF 10 antibody
    • FGF-10 antibody
    • FGF10 antibody
    • FGF10_HUMAN antibody
    • Fibroblast growth factor 10 antibody
    • Keratinocyte growth factor 2 antibody
    • KGF 2 antibody
    • Produced by fibroblasts of urinary bladder lamina propria antibody
    • wu:fd11d03 antibody
    • zgc:109774 antibody
    see all

Anti-FGF10 antibody 画像

  • All lanes : Anti-FGF10 antibody (ab91024) at 1 µg/ml

    Lane 1 : Lung (Human) Tissue Lysate
    Lane 2 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 23 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 160 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 3 minutes

Anti-FGF10 antibody (ab91024) 使用論文

ab91024 has not yet been referenced specifically in any publications.

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