製品の概要

  • 製品名Anti-FGF10 antibody
    FGF10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FGF10
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide corresponding to a sequence at the N-terminal of Human FGF10.

  • ポジティブ・コントロール
    • U87, HeLa, A549, 293T and MCF7 whole cell lysates.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115825 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa.

ターゲット情報

  • 機能Could be a growth factor active in the process of wound healing. Acts as a mitogen in the lung. May act in a manner similar to FGF-7.
  • 関連疾患Defects in FGF10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands (ALSG) [MIM:180920]. ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular and sublingual glands and absence of the lacrimal puncta. The disorder is characterized by irritable eyes, recurrent eye infections, epiphora (constant tearing) and xerostomia (dryness of the mouth), which increases the risk of dental erosion, dental caries, periodontal disease and oral infections.
    Defects in FGF10 are a cause of lacrimo-auriculo-dento-digital syndrome (LADDS) [MIM:149730]; also known as Levy-Hollister syndrome. LADDS is a form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. LADDS is an autosomal dominant syndrome characterized by aplastic/hypoplastic lacrimal and salivary glands and ducts, cup-shaped ears, hearing loss, hypodontia and enamel hypoplasia, and distal limb segments anomalies. In addition to these cardinal features, facial dysmorphism, malformations of the kidney and respiratory system and abnormal genitalia have been reported. Craniosynostosis and severe syndactyly are not observed.
  • 配列類似性Belongs to the heparin-binding growth factors family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BB213776 antibody
    • fd11d03 antibody
    • FGF 10 antibody
    • FGF-10 antibody
    • FGF10 antibody
    • FGF10_HUMAN antibody
    • Fibroblast growth factor 10 antibody
    • Keratinocyte growth factor 2 antibody
    • KGF 2 antibody
    • Produced by fibroblasts of urinary bladder lamina propria antibody
    • wu:fd11d03 antibody
    • zgc:109774 antibody
    see all

Anti-FGF10 antibody 画像

  • All lanes : Anti-FGF10 antibody (ab115825) at 1 µg/ml

    Lane 1 : U87 whole cell lysate
    Lane 2 : HeLa whole cell lysate
    Lane 3 : A549 whole cell lysate
    Lane 4 : 293T whole cell lysate
    Lane 5 : MCF7 whole cell lysate


    Predicted band size : 23 kDa

Anti-FGF10 antibody (ab115825) 使用論文

ab115825 has not yet been referenced specifically in any publications.

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