製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FGD1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide, corresponding to a region within N terminal amino acids 2-51 (HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA) of Human FGD1 (NP_004454).

  • ポジティブ・コントロール
    • Transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab104789 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 107 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape.
  • 組織特異性
    Expressed in fetal heart, brain, lung, kidney and placenta. Less expressed in liver; adult heart, brain, lung, pancreas and skeletal muscle.
  • 関連疾患
    Aarskog-Scott syndrome
    Defects in FGD1 are found in a patient with non-syndromal X-linked mental retardation.
  • 配列類似性
    Contains 1 DH (DBL-homology) domain.
    Contains 1 FYVE-type zinc finger.
    Contains 2 PH domains.
  • ドメイン
    The DH domain is involved in interaction with CCPG1.
  • 細胞内局在
    Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Associated with membrane ruffles and lamellipodia.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AAS antibody
    • Faciogenital dysplasia 1 protein antibody
    • FGD1 antibody
    • FGD1_HUMAN antibody
    • FGDY antibody
    • FYVE RhoGEF and PH domain containing protein 1 antibody
    • FYVE, RhoGEF and PH domain-containing protein 1 antibody
    • Rho/Rac GEF antibody
    • Rho/Rac guanine nucleotide exchange factor FGD1 antibody
    • ZFYVE3 antibody
    • Zinc finger FYVE domain containing protein 3 antibody
    • Zinc finger FYVE domain-containing protein 3 antibody
    see all

画像

  • Anti-FGD1 antibody (ab104789) at 1 µg/ml + Transfected 293T cell lysate at 10 µg

    Predicted band size : 107 kDa

プロトコール

参考文献

ab104789 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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