製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to Fetuin
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment (alpha 2-HS glycoprotein) processed to remove a 40 amino acid residue bridging peptide resulting in the mature form of the protein (Human).

  • ポジティブ・コントロール
    • WB: Human serum or purified Fetuin.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファー
    Preservative: 0.01% Sodium Azide
    Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate. pH 7.2
  • Concentration information loading...
  • 精製度
    IgG fraction
  • 特記事項(精製)
    Ab34505 was purified from monospecific antiserum by a multistep process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab34505 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報
    ELISA: 1/40,000 - 1/200,000.
    WB: 1/10000 - 1/20000. Detects a band of approximately 58 kDa.

    Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.
    • 組織特異性
      Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.
    • 配列類似性
      Belongs to the fetuin family.
      Contains 2 cystatin fetuin-A-type domains.
    • 翻訳後修飾
      Phosphorylation sites are present in the extracelllular medium.
      O- and N-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. N-glycan at Asn-156: Hex5HexNAc4; N-glycan heterogeneity at Asn-176: Hex5HexNAc4 (major) and Hex6HexNAc5 (minor).
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 16G2 antibody
      • A2HS antibody
      • AHS antibody
      • Ahsg antibody
      • Alpha 2 HS glycoprotein antibody
      • Alpha 2 Z globulin antibody
      • Alpha 2HS glycoprotein antibody
      • Alpha-2-HS-glycoprotein chain B antibody
      • Alpha-2-Z-globulin antibody
      • Ba alpha 2 glycoprotein antibody
      • Ba-alpha-2-glycoprotein antibody
      • FETUA antibody
      • FETUA_HUMAN antibody
      • FETUB antibody
      • Fetuin A antibody
      • Fetuin B antibody
      • Fetuin like protein antibody
      • Fetuin-A antibody
      • FetuinA antibody
      • FetuinB antibody
      • Gugu antibody
      • HSGA antibody
      • IRL 685 antibody
      • IRL685 antibody
      • PRO2743 antibody
      see all

    Anti-Fetuin antibody 画像

    プロトコール

    Anti-Fetuin antibody (ab34505) 使用論文

    This product has been referenced in:
    • Kutikhin AG  et al. Apoptosis-mediated endothelial toxicity but not direct calcification or functional changes in anti-calcification proteins defines pathogenic effects of calcium phosphate bions. Sci Rep 6:27255 (2016). WB . Read more (PubMed: 27251104) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab34505.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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