製品の概要

  • 製品名Anti-fetal hemoglobin antibody
    fetal hemoglobin 一次抗体 製品一覧
  • 製品の詳細
    Sheep polyclonal to fetal hemoglobin
  • 特異性By immunoelectrophoresis and ELISA this antibody reacts specifically with human hemoglobin F. No antibody was detected against hemoglobin A1, A2, S or human serum proteins.
  • アプリケーション適用あり: ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla
  • 免疫原

    Human Hemoglobin F

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)The antibody was isolated by affinity chromato-graphy using antigen coupled to agarose beads. Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab19364 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent dilution.
IHC-P 1/20. Antigen retrieval is not essential but may optimise staining. PubMed: 21378008

ターゲット情報

  • 関連性The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'
  • 細胞内局在Cytoplasmic
  • 参照データベース
  • 別名
    • A gamma globin antibody
    • G gamma globin antibody
    • Gamma 1 globin antibody
    • Gamma 2 globin antibody
    • Gamma A hemoglobin antibody
    • Gamma globin antibody
    • Hb F Agamma antibody
    • Hb F Ggamma antibody
    • hbfagamma antibody
    • hbfggamma antibody
    • HBG 1 antibody
    • HBG 2 antibody
    • HBG1 antibody
    • HBG2 antibody
    • HBGA antibody
    • HBGR antibody
    • Hemoglobin gamma 1 chain antibody
    • Hemoglobin gamma 2 chain antibody
    • Hemoglobin gamma A antibody
    • Hemoglobin gamma A chain antibody
    • Hemoglobin gamma G antibody
    • Hemoglobin gamma G chain antibody
    • Hemoglobin gamma regulator of antibody
    • Hemoglobin subunit gamma 1 antibody
    • Hemoglobin subunit gamma 2 antibody
    • HSGGL 1 antibody
    • HSGGL1 antibody
    • Methemoglobin antibody
    • PRO 2979 antibody
    • PRO2979 antibody
    see all

Anti-fetal hemoglobin antibody (ab19364) 使用論文

This product has been referenced in:
  • Wolk M & Martin JE Fetal haemopoiesis marking low-grade urinary bladder cancer. Br J Cancer 107:477-81 (2012). Read more (PubMed: 22735903) »
  • Wolk M & Martin JE Fetal haemoglobin (HbF) as an immunohistochemical tumour marker in bone marrow and spleen. J Clin Pathol 64:645-7 (2011). IHC-P ; Human . Read more (PubMed: 21378008) »

See all 4 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab19364.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"