The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 74 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit (By similarity). May participate in antiinflammatory signaling via its interaction with PTGER4.
組織特異性Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level).
パスウェイProtein modification; protein ubiquitination.
配列類似性Belongs to the fem-1 family. Contains 9 ANK repeats. Contains 2 TPR repeats.