製品の概要

  • 製品名
    Anti-Feline MHC Class II antibody [vpg 3]
  • 製品の詳細
    Mouse monoclonal [vpg 3] to Feline MHC Class II
  • 由来種
    Mouse
  • 特異性
    ab34028 recognises MHC Class II antigens
  • アプリケーション
    適用あり: Flow Cyt, IHC-Fr, IPmore details
    適用なし: IHC-P
  • 種交差性
    交差種: Cat
    非交差種: Human
  • 免疫原

    Tissue/ cell preparation of IL2 dependent feline T cells

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 5-10% Foetal calf serum, Tissue culture supernatant, 0.2M Tris HCl. pH 7.4
  • 精製度
    Tissue culture supernatant
  • ポリ/モノ
    モノクローナル
  • クローン名
    vpg 3
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab34028 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IHC-Fr
IP
  • 追加情報
    FACS: Use 50µl for 106 cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Is unsuitable for IHC-P.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      HLA-DRB1 belongs to the HLA class II beta chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells including B lymphocytes, dendritic cells and macrophages.
    • 細胞内局在
      single-pass type I membrane protein
    • 参照データベース
    • 別名
      • DR 1 antibody
      • MHC class II histocompatability antigen antibody

    参考文献

    This product has been referenced in:
    • Khetarpal SA  et al. A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels. Nat Med 23:1086-1094 (2017). Read more (PubMed: 28825717) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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