製品の概要

  • 製品名Anti-FECH antibody
    FECH 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to FECH
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Human FECH protein (NP_000131.2, amino acids 1-423).

  • ポジティブ・コントロール
    • Human liver tissue lysate. FECH transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88838 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 48 kDa.

ターゲット情報

  • 機能Catalyzes the ferrous insertion into protoporphyrin IX.
  • パスウェイPorphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.
  • 関連疾患Erythropoietic protoporphyria (EPP) [MIM:177000]: A form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. Erythropoietic protoporphyria is marked by excessive protoporphyrin in erythrocytes, plasma, liver and feces, and by widely varying photosensitive skin changes ranging from a burning or pruritic sensation to erythema, edema and wheals. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 配列類似性Belongs to the ferrochelatase family.
  • 細胞内局在Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • EPP antibody
    • FCE antibody
    • Fch antibody
    • Fcl antibody
    • fech antibody
    • Ferrochelatase (protoporphyria) antibody
    • Ferrochelatase antibody
    • Ferrochelatase mitochondrial antibody
    • Heme synthase antibody
    • Heme synthetase antibody
    • HEMH_HUMAN antibody
    • mitochondrial antibody
    • Protoheme ferro lyase antibody
    • Protoheme ferro-lyase antibody
    • Protoporphyria antibody
    see all

Anti-FECH antibody 画像

  • Anti-FECH antibody (ab88838) at 1/500 dilution + human liver tissue lysate at 50 µg

    Predicted band size : 48 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-FECH antibody (ab88838) at 1/500 dilution

    Lane 1 : FECH transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 48 kDa
    Observed band size : 46 kDa (why is the actual band size different from the predicted?)

Anti-FECH antibody (ab88838) 使用論文

ab88838 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"