製品の概要

  • 製品名Anti-FCRL3 antibody
    FCRL3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FCRL3
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen, corresponding to amino acids 602-725 of Human FCRL3.

  • ポジティブ・コントロール
    • Human cerebral cortex tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab121471 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 組織特異性Primarily expressed in secondary lymphoid tissues by mature subsets of B cells. Detected in spleen, lymph node, peripheral blood lymphocytes, thymus, bone marrow, kidney, salivary gland, adrenal gland and uterus. Expressed a low levels in naive, germinal center and memory B cells but also expressed in NK cells (at protein level).
  • 関連疾患Genetic variation in FCRL3 may be a cause of susceptibility to rheumatoid arthritis (RA) [MIM:180300]. It is a systemic inflammatory disease with autoimmune features and a complex genetic component. It primarily affects the joints and is characterized by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures.
    Genetic variation in FCRL3 may influence susceptibility to Graves disease, an autoimmune disorder associated with overactivity of the thyroid gland and hyperthyroidism.
  • 配列類似性Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
  • 翻訳後修飾Phosphorylated on cytoplasmic tyrosines; required for interaction with protein tyrosine phosphatases and protein tyrosine kinases.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD307c antibody
    • Fc receptor homolog 3 antibody
    • Fc receptor-like protein 3 antibody
    • FcR-like protein 3 antibody
    • FcRH3 antibody
    • FcRL3 antibody
    • FCRL3_HUMAN antibody
    • hIFGP3 antibody
    • IFGP family protein 3 antibody
    • IFGP3 antibody
    • Immune receptor translocation-associated protein 3 antibody
    • Immunoglobulin superfamily receptor translocation associated protein 3 antibody
    • IRTA3 antibody
    • SH2 domain-containing phosphatase anchor protein 2 antibody
    • SPAP2 antibody
    see all

Anti-FCRL3 antibody 画像

  • ab121471, at 1/20 dilution, staining FCRL3 in paraffin-embedded Human cerebral cortex tissue, by Immunohistochemistry.

Anti-FCRL3 antibody (ab121471) 使用論文

ab121471 has not yet been referenced specifically in any publications.

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The product which we spoke about on the phone today is actually against the Fc region of human IgG and not against any of the Fc Receptor proteins which you inquiring about. While we do not have a single produ...

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