製品の概要

  • 製品名Anti-FCGR1A antibody [EPR4623]
    FCGR1A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4623] to FCGR1A
  • アプリケーション適用あり: WB, IP, Flow Cytmore details
    適用なし: IHC-P
  • 種交差性
    交差種: Human
  • 免疫原

    A synthetic peptide corresponding to residues in the extracellular domain of Human FCGR1A.

  • ポジティブ・コントロール
    • U937, THP1, and HL60 cell lysates; U937 cells.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab109449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 64-78 kDa (predicted molecular weight: 43 kDa).
IP 1/10 - 1/100.
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 追加情報Is unsuitable for IHC-P.
  • ターゲット情報

    • 機能High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
    • 組織特異性Monocyte/macrophage specific.
    • 配列類似性Belongs to the immunoglobulin superfamily. FCGR1 family.
      Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    • 翻訳後修飾Phosphorylated on serine residues.
    • 細胞内局在Cell membrane. Stabilized at the cell membrane through interaction with FCER1G.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD64 antibody
      • CD64A antibody
      • Fc fragment of IgG high affinity Ia receptor (CD64) antibody
      • Fc fragment of IgG, high affinity Ia, receptor for antibody
      • Fc gamma receptor antibody
      • Fc gamma receptor I A1 antibody
      • Fc gamma RI antibody
      • Fc gamma RIA antibody
      • Fc-gamma RI antibody
      • Fc-gamma RIA antibody
      • FCG1 antibody
      • FcgammaRIa antibody
      • FCGR1 antibody
      • FCGR1_HUMAN antibody
      • FCGR1A antibody
      • FcRI antibody
      • FLJ18345 antibody
      • High affinity immunoglobulin gamma Fc receptor I antibody
      • IGFR1 antibody
      • IgG Fc receptor I antibody
      • Immunoglobulin G Fc receptor I antibody
      • OTTHUMP00000013913 antibody
      see all

    Anti-FCGR1A antibody [EPR4623] 画像

    • All lanes : Anti-FCGR1A antibody [EPR4623] (ab109449) at 1/1000 dilution

      Lane 1 : U937 cell lysate
      Lane 2 : THP1 cell lysate
      Lane 3 : HL60 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 43 kDa
      Observed band size : 64-78 kDa (why is the actual band size different from the predicted?)
    • ab109449 at 1/100 dilution staining FCGR1A in U937 cells by Flow cytometry (shown in red). Rabbit IgG negative control (shown in green).
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-FCGR1A antibody [EPR4623] (ab109449) 使用論文

    ab109449 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab109449.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"