製品の概要

  • 製品名
    Anti-Fc epsilon RI antibody [CRA2] (FITC)
    Fc epsilon RI 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [CRA2] to Fc epsilon RI (FITC)
  • 標識
    FITC. Ex: 493nm, Em: 528nm
  • アプリケーション
    適用あり: ICC, Flow Cyt, Inhibition Assaymore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: FEDSGEYKCQ HQQVNESEPV YLEVFSDWLL LQASAEVVME GQPLFLRCHG WRNWDVYKVI YYKDGEALKY WYENHNISIT NATVEDSG, corresponding to amino acids 85-172 of Human Fc epsilon RI

  • エピトープ
    Amino acids 85-172 of Fc epsilon RI
  • ポジティブ・コントロール
    • CHO/alpha beta gamma cells
  • 特記事項

    [FITC]/[IgG] 8.9

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C.
  • バッファー
    pH: 7.40
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • 精製度
    IgG fraction
  • 特記事項(精製)
    ab122891 was purified from serum free culture medium of mouse hybridoma (CRA2) by propriety chromatography under mild conditions. Filter sterilized
  • ポリ/モノ
    モノクローナル
  • クローン名
    CRA2
  • アイソタイプ
    IgG1
  • 軽鎖の種類
    kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122891 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab106163-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
Inhibition Assay Use at an assay dependent concentration. Inhibition of binding of IgE with Fc epsilon RI

ターゲット情報

  • 機能
    Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
  • 配列類似性
    Contains 2 Ig-like (immunoglobulin-like) domains.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Fc epsilon RI alpha antibody
    • Fc epsilon RI alpha chain antibody
    • Fc epsilon RI alpha-chain antibody
    • Fc fragment of IgE high affinity I receptor for alpha polypeptide antibody
    • Fc fragment of IgE, high affinity I, receptor for, alpha subunit antibody
    • Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide antibody
    • Fc IgE receptor alpha polypeptide antibody
    • Fc IgE receptor, alpha chain antibody
    • Fc IgE receptor, alpha polypeptide antibody
    • Fc of IgE high affinity I receptor for alpha polypeptide antibody
    • Fc-epsilon RI-alpha antibody
    • FCE 1A antibody
    • FCE1A antibody
    • FCER 1A antibody
    • Fcer1a antibody
    • FCERA_HUMAN antibody
    • FceRI alpha antibody
    • FcERI antibody
    • high affinity IgE receptor antibody
    • High affinity immunoglobulin epsilon receptor alpha subunit antibody
    • high affinity immunoglobulin epsilon receptor alpha-subunit antibody
    • High affinity immunoglobulin epsilon receptor subunit alpha antibody
    • IgE Fc receptor alpha subunit antibody
    • IgE Fc receptor subunit alpha antibody
    • Immunoglobulin E receptor high affinity of mast cells alpha polypeptide antibody
    • immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide antibody
    see all

Anti-Fc epsilon RI antibody [CRA2] (FITC) 画像

  • FACS analysis of CHO/alpha beta gamma cells (1x105) with CRA1 and CRA2 antibodies by indirect-immunostaining using FITC-labeled secondary antibody.

Anti-Fc epsilon RI antibody [CRA2] (FITC) (ab122891) 使用論文

This product has been referenced in:
  • Takai T  et al. Direct expression of the extracellular portion of human FcepsilonRIalpha chain as inclusion bodies in Escherichia coli. Biosci Biotechnol Biochem 65:79-85 (2001). Read more (PubMed: 11272849) »
  • Goto T  et al. Enhanced expression of the high-affinity receptor for IgE (Fc(epsilon)RI) associated with decreased numbers of Langerhans cells in the lesional epidermis of atopic dermatitis. J Dermatol Sci 27:156-61 (2001). Read more (PubMed: 11641054) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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