製品の概要

  • 製品名Anti-FBXO7 antibody
    FBXO7 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to FBXO7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: AVCRDLFTAS NDPLLWRFLY LRDFRDNTVR VQDTDWKELY RKRHIQRKES PKGRFVMLLP SSTHTIPFYP NPLHPRPFPS SRLPPGIIGG EYDQRPTLP, corresponding to amino acids 357-456 of Human FBXO7

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5.
    • パスウェイProtein modification; protein ubiquitination.
    • 関連疾患Defects in FBXO7 are the cause of Parkinson disease type 15 (PARK15) [MIM:260300]; also known as parkinsonian-pyramidal syndrome. A neurodegenerative disorder characterized by parkinsonian and pyramidal signs. Clinical manifestations include tremor, bradykinesia, rigidity, postural instability, spasticity, mainly in the lower limbs, and hyperreflexia.
    • 配列類似性Contains 1 F-box domain.
    • 細胞内局在Cytoplasm. Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • F box only protein 7 antibody
      • F box protein 7 antibody
      • F-box only protein 7 antibody
      • FBX antibody
      • FBX07 antibody
      • FBX7 antibody
      • FBX7_HUMAN antibody
      • Fbxo7 antibody
      • PARK15 antibody
      • PKPS antibody
      see all

    Anti-FBXO7 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57037 FBXO7 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-FBXO7 antibody (ab57037) 使用論文

    ab57037 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57037.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"