製品の概要

  • 製品名Anti-FBXO11 antibody
    FBXO11 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to FBXO11
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: KAVSRGQCLY KISSYTSYPM HDFYRCHTCN TTDRNAICVN CIKKCHQGHD VEFIRHDRFF CDCGAGTLSN PCTLAGEPTH DTDTLYDSAP PIESNTLQHN , corresponding to amino acids 744-844 of Human FBXO11

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57812 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Substrate recognition component of the a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of TP53.
    • 組織特異性Isoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.
    • パスウェイProtein modification; protein ubiquitination.
    • 配列類似性Contains 1 F-box domain.
      Contains 19 PbH1 repeats.
      Contains 1 UBR-type zinc finger.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • F box protein 11 antibody
      • F-box only protein 11 antibody
      • FBX11 antibody
      • FBX11_HUMAN antibody
      • Fbxo11 antibody
      • PRMT9 antibody
      • Protein arginine N methyltransferase 9 antibody
      • Ubiquitin protein ligase E3 component n recognin 6 antibody
      • UBR6 antibody
      • UG063H01 antibody
      • VIT-1 antibody
      • VIT1 antibody
      • Vitiligo associated protein VIT 1 antibody
      • Vitiligo-associated protein 1 antibody
      see all

    Anti-FBXO11 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57812 FBXO11 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-FBXO11 antibody (ab57812) 使用論文

    ab57812 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"