製品の概要

  • 製品名Anti-FBXL3 antibody
    FBXL3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to FBXL3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: MKRGGRDSDR NSSEEGTAEK SKKLRTTNEH SQTCDWGNLL QDIILQVFKY LPLLDRAHAS QVCRNWNQVF HMPDLWRCFE FELNQPATSY LKATHPELIK , corresponding to amino acids 1-101 of Human FBXL3 (NP_036290) with a 26kDa enzyme tag

  • ポジティブ・コントロール
    • HeLa cell lysate

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab77200 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).

ターゲット情報

  • 機能Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • 組織特異性Widely expressed.
  • 配列類似性Contains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • 細胞内局在Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • F box and leucine rich repeat protein 3 antibody
    • F box and leucine rich repeat protein 3A antibody
    • F box protein Fbl3a antibody
    • F-box and leucine-rich repeat protein 3A antibody
    • F-box/LRR-repeat protein 3 antibody
    • F-box/LRR-repeat protein 3A antibody
    • FBL3 antibody
    • FBL3A antibody
    • Fbxl3 antibody
    • FBXL3_HUMAN antibody
    • FBXL3A antibody
    see all

Anti-FBXL3 antibody 画像

  • Anti-FBXL3 antibody (ab77200) at 1/500 dilution + HeLa cell lysate at 25 µg

    Secondary
    HRP-conjugated goat anti-mouse IgG at 1/2500 dilution
    Developed using the ECL technique

    Predicted band size : 49 kDa
    Observed band size : 49 kDa
  • Anti-FBXL3 antibody (ab77200) at 1/500 dilution + immunogen (37.11 KDa) at 0.1 µg

    Secondary
    HRP-conjugated goat anti-mouse IgG at 1/5000 dilution
    Developed using the ECL technique

    Predicted band size : 49 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-FBXL3 antibody (ab77200) 使用論文

ab77200 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab77200.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"