製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FBXL3
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Sheep, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within C-terminal amino acids 239-288 (ELLLALSSEK HVRLEHLRID VVSENPGQTH FHTIQKSSWD AFIKHSPKVN) of Mouse FBXL3 (NP_056637).

  • ポジティブ・コントロール
    • Mouse kidney lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab123116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • 組織特異性
    Widely expressed.
  • 配列類似性
    Contains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • 細胞内局在
    Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • F box and leucine rich repeat protein 3 antibody
    • F box and leucine rich repeat protein 3A antibody
    • F box protein Fbl3a antibody
    • F-box and leucine-rich repeat protein 3A antibody
    • F-box/LRR-repeat protein 3 antibody
    • F-box/LRR-repeat protein 3A antibody
    • FBL3 antibody
    • FBL3A antibody
    • Fbxl3 antibody
    • FBXL3_HUMAN antibody
    • FBXL3A antibody
    see all

画像

  • Anti-FBXL3 antibody (ab123116) at 1 µg/ml + Mouse kidney lysate at 10 µg

    Predicted band size : 49 kDa

プロトコール

参考文献

ab123116 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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