製品の概要

  • 製品名Anti-FBXL3 antibody
    FBXL3 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to FBXL3
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Dog
  • 免疫原

    Synthetic peptide:

    KRGGRDSDRNSSEE-C

    , corresponding to N terminal amino acids 2-15 of Human FBXL3.

  • ポジティブ・コントロール
    • Human thyroid tissue; Human adipose lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 49 kDa.
ELISA 1/32000.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex involved in circadian clock function. The SCF(FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.
  • 組織特異性Widely expressed.
  • 配列類似性Contains 1 F-box domain.
    Contains 7 LRR (leucine-rich) repeats.
  • 細胞内局在Nucleus. Cytoplasm. Predominantly nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • F box and leucine rich repeat protein 3 antibody
    • F box and leucine rich repeat protein 3A antibody
    • F box protein Fbl3a antibody
    • F-box and leucine-rich repeat protein 3A antibody
    • F-box/LRR-repeat protein 3 antibody
    • F-box/LRR-repeat protein 3A antibody
    • FBL3 antibody
    • FBL3A antibody
    • Fbxl3 antibody
    • FBXL3_HUMAN antibody
    • FBXL3A antibody
    see all

Anti-FBXL3 antibody 画像

  • ab115515, at 5µg/ml staining FBXL3 in formalin-fixed, paraffin-embedded Human thyroid tissue by Immunohistochemistry, using a biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-FBXL3 antibody (ab115515) at 1 µg/ml + Human adipose lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 49 kDa

Anti-FBXL3 antibody (ab115515) 使用論文

ab115515 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"