製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to FBP2
  • 特異性
    The immunogen for this antibody has 84% alignment with the FBP1 protein. It is therefore likely that this antibody could detect FBP1 as well as FBP2.
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Saccharomyces cerevisiae, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 (YAKYFDAATT EYVQKKKFPE DGSAPYGARY VGSMVADVHR TLVYGGIFLY) of Human FBP2 (NP_003828).

  • ポジティブ・コントロール
    • Human fetal muscle lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 37 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
  • 組織特異性
    Expressed in skeletal muscle (at protein level).
  • パスウェイ
    Carbohydrate biosynthesis; gluconeogenesis.
  • 配列類似性
    Belongs to the FBPase class 1 family.
  • 細胞内局在
    Cell junction. Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere, Z line. In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 6-bisphosphatase isozyme 2 antibody
    • 6-bisphosphate 1-phosphohydrolase 2 antibody
    • D fructose 1 6 bisphosphate 1 phosphohydrolase 2 antibody
    • D-fructose-1 antibody
    • F16P2_HUMAN antibody
    • FBP 2 antibody
    • fbp2 antibody
    • FBPase 2 antibody
    • FBPase antibody
    • fructose 1 6 bisphosphatase 2 antibody
    • Fructose 1 6 bisphosphatase isozyme 2 antibody
    • Fructose-1 antibody
    • Hexosediphosphatase antibody
    • MGC142192 antibody
    • Muscle FBPase antibody
    • Muscle fructose bisphosphatase antibody
    see all

画像

  • Anti-FBP2 antibody (ab84566) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

プロトコール

参考文献

ab84566 has not yet been referenced specifically in any publications.

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