製品の概要

  • 製品名Anti-FBLIM1 antibody
    FBLIM1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to FBLIM1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of Human FBLIM1 (NP_001019387.1 , NP_001019386.1 , NP_060026.2).

  • ポジティブ・コントロール
    • A549 cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab112590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

ターゲット情報

  • 機能Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly.
  • 組織特異性Isoform 1 and isoform 3 are expressed in heart, kidney, lung, pancreas, placenta and platelets. Isoform 2 is expressed in brain, heart, kidney, lung, pancreas, placenta, skeletal muscle and platelets.
  • 配列類似性Contains 3 LIM zinc-binding domains.
  • 細胞内局在Cytoplasm > cell cortex. Cell junction > focal adhesion. Cytoplasm > cytoskeleton. Associated with actin stress fiber at cell-ECM focal adhesion sites. Isoform 1 and isoform 3 are recruited and localized at actin stress fibers and clustered at cell-EMC adhesion sites through interaction with PLEKHC1. Isoform 2 is localized at actin stress fibers.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 2410043F08Rik antibody
    • Cal antibody
    • CSX associated LIM antibody
    • DKFZp434G171 antibody
    • FBLI1_HUMAN antibody
    • FBLIM 1 antibody
    • Fblim1 antibody
    • FBLP 1 antibody
    • FBLP-1 antibody
    • FBLP1 antibody
    • Filamin binding LIM protein 1 antibody
    • Filamin-binding LIM protein 1 antibody
    • Gt10 antibody
    • MGC105665 antibody
    • MIG2 interacting protein; antibody
    • MIG2-interacting protein antibody
    • Migfilin antibody
    • Mitogen inducible 2 interacting protein antibody
    • Mitogen-inducible 2-interacting protein antibody
    • OTTHUMP00000003118 antibody
    • OTTHUMP00000003119 antibody
    • OTTHUMP00000003120 antibody
    • OTTMUSP00000011062 antibody
    • OTTMUSP00000011063 antibody
    • RP11-169K16.5 antibody
    • RP23-291H3.1 antibody
    see all

Anti-FBLIM1 antibody 画像

  • Anti-FBLIM1 antibody (ab112590) at 1/100 dilution + A549 cell line lysate at 35 µg

    Predicted band size : 41 kDa

Anti-FBLIM1 antibody (ab112590) 使用論文

ab112590 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Mouse Cell (Mouse Embryonic Fibroblast (MEF))
Specification Mouse Embryonic Fibroblast (MEF)
Fixative Paraformaldehyde
Permeabilization Yes - triton
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投稿 Nov 16 2011

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HeLa cell line ( cervical cancer))
Specification HeLa cell line ( cervical cancer)
Fixative Paraformaldehyde
Permeabilization Yes - triton
Username

Abcam user community

Verified customer

投稿 Nov 16 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"