製品の概要

  • 製品名
    Anti-FAT antibody [Fat-1]
    FAT 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [Fat-1] to FAT
  • アプリケーション
    適用あり: WB, ICC/IF, ELISAmore details
  • 種交差性
    交差種: Drosophila melanogaster
    交差が予測される動物種: Rat, Chimpanzee
  • 免疫原

    Cytoplasmic domain of drosphila FAT 1

  • ポジティブ・コントロール
    • Wild type imaginal discs from third instar larva

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab20163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ICC/IF
ELISA
  • 追加情報
    ELISA: Use at an assay dependent dilution.
    IF: Use at an assay dependent dilution.
    WB: Use 3-8% gradient gels to visualise the FAT protein and wet transfer. Predicted molecular weight: 506 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Plays an essential role for cellular polarization, directed cell migration and modulating cell-cell contact.
    • 組織特異性
      Expressed in many epithelial and some endothelial and smooth muscle cells.
    • 配列類似性
      Contains 33 cadherin domains.
      Contains 5 EGF-like domains.
      Contains 1 laminin G-like domain.
    • ドメイン
      A PTB-like motif (DNXYH sequence) is required for the targeting to the leading edge. This motif represents a minimal protein-protein interaction core motif that is not regulated by tyrosine phosphorylation.
    • 翻訳後修飾
      Undergoes proteolytic cleavage. The extracellular domain is cleaved off and the cytoplasmic domain (about 400 AA) shuttles to the nucleus.
    • 細胞内局在
      Cell membrane. Nucleus. Cytoplasm > perinuclear region.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cadherin family member 7 antibody
      • Cadherin family member 7 precursor antibody
      • Cadherin ME5 antibody
      • Cadherin related tumor suppressor antibody
      • Cadherin related tumor suppressor homolog antibody
      • Cadherin related tumor suppressor homolog precursor antibody
      • Cadherin related tumor suppressor homolog precursor (FAT protein homolog) antibody
      • Cadherin-related tumor suppressor homolog antibody
      • CDHF 7 antibody
      • CDHF7 antibody
      • FAT 1 antibody
      • FAT tumor suppressor 1 antibody
      • FAT tumor suppressor homolog 1 antibody
      • FAT1 antibody
      • FAT1_HUMAN antibody
      • hFat 1 antibody
      • hFAT antibody
      • hFat1 antibody
      • Homolog of Drosophila FAT protein antibody
      • Homolog of Drosophila FAT protein precursor antibody
      • Homolog of Drosophila tumor suppressor FAT precursor antibody
      • ME 5 antibody
      • ME5 antibody
      • nuclear form antibody
      • Protein fat homolog antibody
      • Protocadherin Fat 1 antibody
      see all

    参考文献

    This product has been referenced in:
    • Huang JW  et al. Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity. Mol Cancer Res 11:1564-73 (2013). Read more (PubMed: 24088786) »

    See 1 Publication for this product

    レビューと Q&A

    Thank you for contacting us. This product has not been tested in human. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    登録